When asked on NBC’s “Meet the Press,” Republican National Committee chairman Reince Priebus said “Hillary Clinton’s age and health are valid campaign issues” should she opt to run for the presidency in 2016.

The question picked up on comments by Karl Rove suggesting Hillary Clinton may have suffered brain damage in 2012.

“I think that health and age is fair game,” Priebus said. “It was fair game for Ronald Reagan. It was fair game for John McCain.”

Priebus did not say he thought Rove should apologize for raising the topic. Meanwhile, former NYC Mayor Michael Bloomberg denounced the comments on CBS.

Clinton suffered a blood clot in her head in December 2012 after falling at her home and received several days of treatment at a New York hospital. The incident raised health concerns for Clinton, who was a widely traveled secretary of state during President Barack Obama’s first term.

Former New York City Mayor Michael Bloomberg blasted Rove’s comments as beyond the pale. “I thought his remarks just were outrageous,” he said on CBS’s “Face the Nation” on Sunday.

Bloomberg called Clinton a “great American” who would make a “spectacular candidate on the Democratic side.”